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The most common adverse reactions 15 observed in prograf-treated heart transplant patients are abnormal renal function, hypertension, diabetes mellitus, cmv infection, tremor, hyperglycemia, leukopenia, infection, anemia, bronchitis, pericardial effusion, urinary tract infection and hyperlipemia.

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Dosing should be titrated based on clinical assessments of rejection and tolerabilityLower Prograf dosages than the recommended initial dosage may be sufficient as maintenance therapyAdjunct therapy with adrenal corticosteroids is recommended early post-transplant.

Prograf injection should be reserved for patients unable to take Prograf capsules orallysee DOSAGE AND ADMINISTRATION and WARNINGS AND PRECAUTIONS

Medicines are sometimes prescribed for purposes other than those listed in the Patient InformationDo not use PROGRAF for a condition for which it was not prescribedDo not give PROGRAF to other peopleeven if they have the same symptoms that you haveIt may harm themYou can ask your pharmacist or healthcare provider for information about PROGRAF that is written for health professionals.

It is important to take Prograf capsules consistently every day either with or without food because the presence and composition of food decreases the bioavailability of Prografsee CLINICAL PHARMACOLOGY

Prograf can harm your kidneysand this effect is increased when you also use certain other medicines harmful to the kidneysBefore using Prograftell your doctor about all other medicines you useMany other drugsincluding some over-the-counter medicinescan be harmful to the kidneys.

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the overall 1-year graft survival csa aza and prograf-based treatment groups combined was 81 in the u.

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