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Thyroid replacement is a lifelong treatment, which means that you will have to take levothroid or other levothyroxine tablets for the rest of your life.

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Thyroid hormone synthesis and secretion is regulated by the hypothalamic-pituitary-thyroid axisThyrotropin-releasing hormoneTRHreleased from the hypothalamus stimulates secretion of thyrotropin-stimulating hormoneTSHfrom the anterior pituitaryTSHin turnis the physiologic stimulus for the synthesis and secretion of thyroid hormonesL-thyroxineT 4and L-triiodothyronineT 3by the thyroid glandCirculating serum T 3 and T 4 levels exert a feedback effect on both TRH and TSH secretionWhen serum T 3 and T 4 levels increaseTRH and TSH secretion decreaseWhen thyroid hormone levels decreaseTRH and TSH secretion increase.

Levothyroxine treats hypothyroidismlow thyroid hormoneLevothyroxine is also used to treat or prevent goiterenlarged thyroid glandwhich can be caused by hormone imbalancesradiation treatmentsurgeryor cancer.

Noteif you are prescribed levothyroxine in capsule formyou must swallow them wholeNever crush these capsules.

Use levothyroxine only as prescribed by your physicianDo not discontinue or change the amount you take or how often you take itunless directed to do so by your physician.

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