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Read this medication guide before you start using sinemet sr and each time you get a refill.

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All patients should be observed carefully for the development of depression with concomitant suicidal tendencies.

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Do not give SINEMET to anyone elseeven if they have the same condition as you.

SINEMET should be administered cautiously to patients with severe cardiovascular or pulmonary diseasebronchial asthmarenalhepatic or endocrine disease.

These medicines may be affected by SINEMETor may affect how well the tablets workYou may need different amounts of your medicineor you may need to take different medicines.

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