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How much colchicine for gout

Colchicine and probenecid may also be used for purposes other than those listed in this medication guide.

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Information about Colchicine.

Colchicine is not a pain medication and should not be used to relieve other causes of pain.

Colchicine has been reported to cause neuromuscular toxicitywhich may present as muscle pain or weaknesssee WARNINGS AND PRECAUTIONS

The first stage of acute colchicine toxicity typically begins within 24 hours of ingestion and includes gastrointestinal symptoms such as abdominal painnauseavomitingdiarrheaand significant fluid lossleading to volume depletionPeripheral leukocytosis may also be seenLife-threatening complications occur during the second stagewhich occurs 24 to 72 hours after drug administrationattributed to multi-organ failure and its associated consequencesDeath usually results from respiratory depression and cardiovascular collapseIf the patient survivesrecovery of multi-organ injury may be accompanied by rebound leukocytosis and alopecia starting about 1 week after the initial ingestionTreatment of colchicine overdose should begin with gastric lavage and measures to prevent shockOtherwisetreatment is symptomatic and supportiveNo specific antidote is knownColchicine is not effectively removed by hemodialysisSee Pharmacokinetics

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yes, colchicine is a potentially dangerous drug, especially in overdose.

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