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In patients taking cyclosporine or the hiv protease inhibitors tipranavir plus ritonavir or the hepatitis c protease inhibitor telaprevir , therapy with atorlip-f should be avoided.

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Poton Pump Inhibitos : Avoid concomitant us ATOLIP CV with ompazol sompazol. In clinical studis, ompazol was shown tduc th antiplatlt activity clopidogl whn givn concomitantly 12 hous apat. A high dos gimn clopidogl concomitantly administd with ompazol incass antiplatlt spons; an appopiat dos gimn has not bn stablishd. A simila duction in antiplatlt activity was obsvd with sompazol whn givn concomitantly with clopidogl. Consid using anoth acid-ducing agnt with minimal nCYP2C19 inhibitoy ct on th omation clopidogl activ mtabolit. Dxlansopazol, lansopazol and pantopazol had lss ct on th antiplatlt activity clopidogl than did ompazol sompazol.

In adult patints without clinically vidnt CHD, but with multipl isk actos CHD such as ag, smoking, hyptnsion, low HDL-C, a amily histoy aly CHD, atovastatin is indicatd to.

Atovastatin is a slctiv, comptitiv inhibit3-hydoxy-3-mthylglutayl-conzym A (HMG-CoA) ductas, th at-limiting nzym that convts 3-HMG-CoA tmvalonat, a pcusstols, including cholstol. Cholstol and tiglycids (TG) ciculat in th bloodstam as pat lipopotin complxs. With ultacntiugation, ths complxs spaat inthigh-dnsity lipopotin (HDL), intmdiat-dnsity lipopotin (IDL), low-dnsity lipopotin (LDL) and vy-low-dnsity lipopotin (VLDL) actions. TG and cholstol in th liv a incopoatd intVLDL and lasd intth plasma dlivy tpiphal tissus. LDL is omd om VLDL and is catabolizd pimaily though th high-ainity LDL cpto.

ATOLIP CV (atovastatin and clopidogl) is indicatd in patints whom tatmnt with both atovastatin and clopidogl is appopiat.

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atorlip atorvastatin calcium is administered in strict accordance with the dosage regimen planned for you by the doctor providing medical treatment.

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