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Medications similar to cilostazol have caused seriouspossibly fatalproblems in people with a certain type of heart diseaseheart failureThereforedo not use cilostazol if you have heart failure.

In addition to reporting episodes of bleeding and easy bruisingpatients should be warned to promptly report any other signs which might also suggest the early development of blood dyscrasia such as pyrexia and sore throatA full blood count should be performed if infection is suspected or there is any other clinical evidence of blood dyscrasiaCilostazol should be discontinued promptly if there is clinical or laboratory evidence of haematological abnormalities.

Patients should be warned to report any episode of bleeding or easy bruising whilst on therapyIn case of retinal bleeding administration of cilostazol should be stoppedRefer to sections 4.3 and 4.5 for further information on bleeding risks.

Figure 2Percent Mean Improvement in Maximal Walking Distance at Study End for the Eight RandomizedDouble-BlindPlacebo-Controlled Clinical Trials.

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